The Rubella IgG & IgM ELISA (Enzyme-Linked Immunosorbent Assay) test is a blood test that detects antibodies against the rubella virus.
Rubella, commonly known as German measles, is a contagious viral infection that is particularly concerning for pregnant women due to the risk of congenital rubella syndrome (CRS), which can cause severe birth defects. Detecting IgG and IgM antibodies helps determine if a person has immunity to rubella, a recent or past infection, or no immunity at all.
1. Rubella IgG Antibodies:
These antibodies appear after infection or vaccination and provide long-term immunity against the rubella virus.
A positive IgG result generally indicates past exposure to rubella or successful immunization.
2.Normal IgG Range: Typically, the presence of IgG antibodies above 10 IU/mL suggests immunity. However, ranges may vary slightly depending on the laboratory.
2. Rubella IgM Antibodies:
IgM antibodies are the body's initial response to rubella infection and usually appear within a few days to weeks after exposure.
A positive IgM result indicates a recent or active rubella infection.
IgM levels generally decrease after the initial infection period and are not long-lasting.
IgG Positive / IgM Negative: This result usually indicates past infection or successful vaccination and immunity to rubella.
IgG Negative / IgM Positive: Indicates a recent or active rubella infection. This is especially significant in pregnant women, as it implies a risk of transmission to the fetus.
IgG Positive / IgM Positive: Suggests a recent rubella infection or reactivation, though false positives can occur. Additional testing may be required to confirm.
IgG Negative / IgM Negative: Indicates no previous exposure, no immunity, and a susceptibility to rubella infection.
1.Sample Collection: A blood sample is drawn from a vein in the arm.
ELISA Methodology: The test uses the ELISA method to detect rubella IgG and IgM antibodies.
Interpretation: Results are interpreted by comparing the antibody levels in the sample to standardized reference values.
Prenatal Screening: Determines immunity to rubella in pregnant women to assess the risk of CRS in case of exposure.
Diagnosis of Acute Rubella Infection: Helps in diagnosing rubella infection during a recent outbreak or in patients with symptoms of rubella.
Vaccination Confirmation: Confirms immunity post-vaccination in cases where immunity is necessary, such as before pregnancy.
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1. Advanced Technology:: Diagnopein uses advanced ELISA technology to ensure highly accurate and reliable test results.
2. Comprehensive Reporting:: Clear, detailed reports on both IgG and IgM levels for easy understanding and medical follow-up.
3. Expertise in Infectious Disease Testing:: Experienced lab technicians and pathologists specializing in infectious disease diagnostics ensure precision and accuracy.
4. Affordable and Efficient:: Cost-effective testing with quick turnaround times to ensure timely diagnosis and treatment.
5. Personalized Patient Care:: Supportive staff dedicated to assisting with queries and offering guidance on test interpretations and next steps.
Yes, vaccination is recommended for those who are not immune, especially for women of childbearing age who are not pregnant.
It assesses immunity against rubella and the risk of CRS, which can lead to severe fetal complications if contracted during pregnancy.
There is no specific treatment for rubella; however, symptoms are generally managed, and preventive measures can protect uninfected individuals.
This indicates a recent infection. It’s essential to avoid pregnancy and consult a healthcare provider for guidance.
IgM antibodies generally disappear within a few weeks to months post-infection. However, detection duration may vary. IgM antibodies generally disappear within a few weeks to months post-infection. However, detection duration may vary.
