The GAD 65 test is an important diagnostic tool used to identify the presence of antibodies against the enzyme glutamic acid decarboxylase (GAD), specifically the GAD 65 isoform.
This enzyme is crucial in the synthesis of the neurotransmitter gamma-aminobutyric acid (GABA), which plays a vital role in regulating neuronal excitability in the brain. The presence of GAD 65 antibodies is often associated with autoimmune conditions, particularly Type 1 diabetes and other autoimmune disorders.
The Anti GAD 65 antibody test measures the levels of GAD antibodies in the blood. This test is particularly useful for diagnosing autoimmune diabetes and is often ordered when a patient presents with symptoms of diabetes, such as increased thirst, frequent urination, fatigue, and unexplained weight loss. In addition to diabetes, the test may also be relevant for individuals with other autoimmune conditions, including:
1] Latent autoimmune diabetes in adults (LADA)
2] Autoimmune encephalitis
3] Graves' disease
The results of the GAD 65 test are usually given in units per milliliter (U/mL). The GAD 65 test normal range can vary slightly depending on the laboratory, but it generally falls within the following parameters:
1] Negative: Less than 5.0 U/mL
2] Indeterminate: 5.0 to 10.0 U/mL
3] Positive: Greater than 10.0 U/mL
Interpreting the results of the GAD 65 test involves understanding what different levels of antibodies mean for your health.
1] Negative Result - A negative result (less than 5.0 U/mL) typically means that there are no GAD 65 antibodies detected in your blood. This is usually a good sign, indicating that your immune system is not attacking the GAD enzyme.
2] Indeterminate Result - An indeterminate result (5.0 to 10.0 U/mL) suggests that the levels of GAD 65 antibodies are borderline. In such cases, your doctor may recommend further testing or monitoring over time to see if the antibody levels change.
3] Positive Result - A positive result (greater than 10.0 U/mL) indicates a high level of GAD 65 antibodies. This is often a sign of an autoimmune response, which could be linked to Type 1 Diabetes or a neurological disorder. Your healthcare provider will discuss what this means for your health and the next steps you should take.
At Diagnopein, we offer comprehensive, accurate, and timely diagnostic services, including the GAD 65 IgG Antibody test pune. With our NABL-accredited labs, cutting-edge technology, and skilled technicians, you can be assured of reliable results every time. Get your results quickly, especially when time is crucial in detecting severe infections.
Competitive pricing without compromising on quality. Our team of experienced professionals ensures the test is conducted smoothly with minimal discomfort. We provide not just GAD 65 IgG test results but insights into your health condition, helping you and your doctor make informed decisions about treatment. For more information call us at +91 9204 108108.
The risks associated with the GAD 65 test are minimal, similar to any standard blood test. These may include slight discomfort, bruising, or infection at the puncture site, though these are rare.
The test is primarily used to diagnose autoimmune diabetes (Type 1 diabetes and LADA). It can also help identify other autoimmune disorders such as autoimmune encephalitis and certain thyroid conditions like Graves’ disease.
A negative GAD 65 test typically means there is no autoimmune activity related to GAD antibodies. However, the absence of these antibodies does not entirely rule out Type 1 diabetes or other autoimmune conditions. Other tests and evaluations may still be required.
The GAD 65 test is a simple blood test. A blood sample is drawn from a vein and then analyzed in a laboratory for the presence and levels of GAD antibodies.
