The Anti-DS DNA (Double-Stranded DNA) Antibody Test is an important diagnostic tool primarily used to detect autoimmune disorders, specifically systemic lupus erythematosus (SLE).
The anti-dsDNA test detects antibodies against double-stranded DNA in the blood. These antibodies are autoantibodies, which are typically absent in a healthy individual, but when present, they are a marker of an autoimmune reaction. A positive anti-dsDNA test is often associated with autoimmune diseases and can be crucial in diagnosing lupus.
Diagnosing Lupus: This test is a major criterion for diagnosing lupus, as anti-dsDNA antibodies are highly specific to this condition.
Assessing Disease Activity: High levels of anti-dsDNA antibodies often correlate with active disease and may indicate a risk of lupus nephritis, a serious complication affecting the kidneys.
Monitoring Autoimmune Disorders: Levels of anti-dsDNA antibodies may fluctuate with disease activity, so the test can help in monitoring the effectiveness of treatment and in making treatment adjustments.
Evaluating Other Autoimmune Conditions: While rare, anti-dsDNA antibodies may be detected in other autoimmune diseases. It’s generally used with other tests to confirm a diagnosis.
The normal range for anti-dsDNA antibodies depends on the laboratory standards, but levels below 25 IU/mL are generally considered normal.
Positive Anti-dsDNA Test: A positive test indicates the presence of anti-dsDNA antibodies, with elevated levels suggesting autoimmune activity, particularly in lupus.
Negative Anti-dsDNA Test: A negative result indicates an absence of these antibodies, reducing the likelihood of lupus but not ruling out other autoimmune diseases.
Positive Anti-dsDNA Test: A positive result often confirms an autoimmune condition, particularly lupus. Higher antibody levels correlate with more severe disease activity.
Negative Anti-dsDNA Test: A negative result suggests no detectable anti-dsDNA antibodies, which typically exclude lupus but do not entirely rule out the presence of other autoimmune diseases.
Anti-DNA Test Normal Range: Generally, <25 IU/mL, although it varies slightly between labs.
While positive anti-dsDNA levels are linked to lupus and other autoimmune diseases, they are not generally indicative of cancer. In rare cases, some cancers may show elevated antibody levels, but these are not specific to cancer and do not confirm a cancer diagnosis.
Individuals with Lupus Symptoms: Those experiencing symptoms like joint pain, fatigue, or skin rashes should consider this test for lupus confirmation.
People with Positive ANA Results: A positive ANA (antinuclear antibody) test often leads to more specific tests like anti-dsDNA to confirm or rule out lupus.
Individuals with Family History of Autoimmune Disorders: Those with relatives diagnosed with lupus or other autoimmune diseases may benefit from early testing.
Patients Undergoing Lupus Treatment: Regular testing helps monitor disease activity and the effectiveness of lupus treatment.
When choosing Diagnopein Diagnostics in Pune for your Anti-DS DNA test in Pune
1. High-Quality Laboratory Standards: Diagnopein adheres to the highest quality standards, ensuring precise, reliable results for all autoimmune tests.
2. Experienced Staff and Specialists: Our trained professionals have extensive experience in interpreting autoimmune test results and guiding patients on their health journey.
3. Advanced Technology: Diagnopein uses state-of-the-art technology, ensuring accurate detection of anti-dsDNA antibodies for early and accurate diagnosis.
4. Affordable Pricing: We provide transparent pricing with no hidden charges, making tests like the anti-dsDNA test price competitive and accessible.
5. Comprehensive Care: Diagnopein offers follow-up consultations, helping you understand your test results and next steps.
6. Convenient Locations and Timely Service: Our centers are conveniently located, providing timely results to aid in swift diagnosis and treatment.
A negative test indicates an absence of anti-dsDNA antibodies, which reduces the likelihood of lupus but does not entirely rule out other autoimmune diseases.
Anti-dsDNA is primarily associated with autoimmune diseases, especially lupus. It is not typically used to diagnose or indicate cancer.
The normal range for anti-dsDNA is typically below 25 IU/mL, although this can vary between labs.
Anti-dsDNA is specific to lupus, while other antibodies, like ANA, may indicate a range of autoimmune conditions. Anti-dsDNA is often ordered after a positive ANA test to confirm lupus.
A positive anti-dsDNA indicates autoimmune activity and could mean active lupus. High levels may also suggest complications like lupus nephritis, affecting the kidneys.
A positive result indicates the presence of anti-dsDNA antibodies, often linked to lupus or other autoimmune conditions. It may suggest active disease, particularly in lupus patients.
