Anti-thrombin III Activity is a blood test that measures the function of antithrombin III, a protein that helps regulate blood clotting by inhibiting thrombin and other clotting factors.
The Anti-Thrombin III Activity Test measures how well AT III is functioning in the bloodstream. AT III is a protein that naturally inhibits enzymes involved in clotting, preventing excessive clot formation. Low levels or activity of antithrombin III can increase the risk of thrombosis, leading to conditions such as deep vein thrombosis (DVT) or pulmonary embolism. This test is often used to evaluate patients with unexplained blood clots or to monitor individuals with known thrombotic disorders.
Normal Range: Typically, the AT III activity level falls between 80-120%. This range represents the percentage of clotting inhibition under standard conditions.
Low Anti-Thrombin III Activity: Levels below the normal range can increase the risk of clot formation, which is often indicative of Antithrombin III deficiency or other underlying conditions.
High Anti-Thrombin III Activity: While rare, higher-than-normal AT III activity can be linked to certain inflammatory or liver conditions and does not typically increase clotting risk.
Hereditary Antithrombin III Deficiency: A genetic disorder where AT III is deficient, leading to a higher risk of blood clots.
Liver Disease: The liver produces AT III, so liver dysfunction can lower AT III activity.
Disseminated Intravascular Coagulation (DIC): This condition consumes AT III faster than the body can produce it.
Acute Infections or Inflammatory States: These conditions can impact the body’s ability to produce AT III.
High AT III activity is rare but may occur with:
Chronic Inflammatory Conditions: Some inflammatory conditions may lead to elevated AT III levels.
Certain Medications: Certain drugs, especially anti-inflammatory medications, might slightly increase AT III levels.
The Anti-Thrombin III Activity Test is often recommended for individuals with:
Unexplained Blood Clots: It helps identify clotting issues not explained by other factors.
Family History of Clotting Disorders: A family history of Antithrombin III deficiency may prompt this test.
Chronic Liver Disease: Liver disease impacts AT III production, so activity testing can help in monitoring.
Choosing Diagnopein Diagnostic Center ensures a reliable and comfortable testing experience. Here’s why Diagnopein in Pune is the ideal choice:
1. NABL Certified Lab: Our NABL-accredited facility adheres to the highest standards of accuracy and quality.
2. Advanced Technology: Diagnopein uses cutting-edge technology for precise AT III activity testing.
3. Experienced Staff: Our skilled staff ensures that tests are conducted with accuracy and attention to patient comfort.
4. Affordable Cost: Diagnopein’s competitive pricing makes quality healthcare accessible.
5. Clean & Hygienic Environment: We prioritize hygiene and comfort for all our patients.
Yes, some medications can impact AT III levels, especially during heparin therapy.
Typically, fasting is not required, but follow any specific instructions provided by your healthcare provider.
Diagnopein generally provides test results within a few days
Symptoms include unexplained blood clots, swelling, and pain in the limbs, usually occurring without other identifiable causes.
Low AT III activity levels increase the risk of blood clot formation and may indicate an underlying deficiency or liver disease.
