Frozen HPE (Histopathological Examination) is a rapid biopsy analysis used to diagnose tissue abnormalities during surgery.
A Frozen HPE (Histopathological Examination), commonly known as a Frozen Section, is a rapid diagnostic test used during surgeries to provide immediate tissue analysis. This technique involves quick-freezing a tissue sample and examining it under a microscope to determine if a disease, like cancer, is present and whether it has spread. Frozen HPE is particularly valuable in guiding surgeons’ decisions during the procedure, allowing them to adjust the surgery based on real-time results.
The Frozen HPE test allows pathologists to analyze a tissue sample in real-time by rapidly freezing it, slicing it into thin sections, staining it, and examining it microscopically. This is useful for:
Detecting cancerous cells: It helps determine if a tumor is benign or malignant.
Evaluating tissue margins: Assesses if the surgical removal is complete by examining the edges of the removed tissue.
Guiding intraoperative decisions: Real-time analysis helps surgeons decide whether additional tissue needs removal.
Frozen HPE is particularly important during surgeries for breast, thyroid, gastrointestinal, and certain brain tumors, where quick, accurate information can change the course of the operation.
A Frozen HPE test may be recommended for individuals undergoing surgery to remove:
Tumors: To check if the tumor is cancerous and if all cancerous tissue has been removed.
Lymph nodes: To determine if cancer has spread to nearby lymph nodes.
Other suspicious growths: To verify the nature of abnormal tissue growths.
The decision to perform a Frozen HPE is typically made by the surgeon based on the nature of the surgery and the suspected diagnosis.
Diagnopein offers expert frozen section services with highly skilled pathologists and advanced laboratory technology to ensure rapid and accurate results. Diagnopein’s commitment to quality, clean facilities, and attention to patient safety makes it a trusted choice for Frozen HPE. This real-time diagnostic service enables effective and informed surgical decisions, minimizing the need for additional surgeries.
No, the test is performed on tissue removed during surgery, so patients do not feel anything specific to this procedure.
Frozen HPE provides rapid results during surgery, whereas a regular biopsy typically takes several days to process and analyze.
The entire process typically takes about 15–30 minutes, depending on the complexity of the tissue sample.
While Frozen HPE is highly accurate, it is usually followed by a more detailed paraffin-embedded histopathology examination for confirmation.
