The HB electrophoresis test, also known as hemoglobin electrophoresis, is a specialized blood test that separates and identifies different types of hemoglobin in the blood.
Hemoglobin is a protein in red blood cells that carries oxygen throughout the body. The HB electrophoresis blood test uses an electrical field to separate hemoglobin into its various types based on their electrical charges and sizes. This separation helps in identifying abnormal hemoglobin types that may indicate certain genetic disorders.
The HB electrophoresis test results are crucial in diagnosing and managing several blood disorders:
1] Sickle Cell Anemia: Characterized by the presence of an abnormal type of hemoglobin called Hemoglobin S (HbS).
2] Thalassemia: Often involves abnormal levels of Hemoglobin A2 (HbA2) or an increased amount of Hemoglobin F (HbF).
3] Hemoglobin C Disease: Identified by the presence of Hemoglobin C (HbC).
Abnormal results can indicate the presence of these conditions or other hemoglobin-related disorders. Your healthcare provider will use the results to recommend appropriate treatment or further diagnostic evaluation.
The normal range for HB electrophoresis test can vary depending on age, sex, and specific laboratory standards. Typically, the normal range for adult hemoglobin types includes:
1] Hemoglobin A (HbA): 95-98%
2] Hemoglobin A2 (HbA2): 2-3%
3] Hemoglobin F (HbF): Less than 1%
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1. Haemoglobin
2. RBC Count
3. MCV
4. RDW-CV
5. Foetal Haemoglobin (HbF)
6. Haemoglobin A0 (Hb A0)
7. Haemoglobin A2 (HbA2)
8. Haemoglobin D (HbD)
9. Haemoglobin S (HbS)
10. Haemoglobin C (HbC)
11. Impression
12. Image FOR HB ELECTRO
The test involves taking a blood sample from a vein, which is then processed in a laboratory using electrophoresis techniques. This process separates different types of hemoglobin based on their charge and size, allowing for their identification and quantification.
There are several types of HB electrophoresis blood tests, including routine hemoglobin electrophoresis, high-performance liquid chromatography (HPLC), capillary electrophoresis, and isoelectric focusing (IEF). Each method provides varying levels of detail and precision.
No special preparation is usually required for an HB electrophoresis test. However, it is advisable to follow any specific instructions provided by your healthcare provider or the laboratory conducting the test.
Yes, HB electrophoresis can be performed during pregnancy to screen for hemoglobin disorders, especially if there is a family history or risk factors present. Your healthcare provider will determine the appropriateness of the test based on your medical history and current health status.
